Premedication with Oral Midazolam in Children—an Assessment of Psychomotor Function, Anxiolysis, Sedation and Pharmacokinetics

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Premedication of children with oral midazolam.

In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of oral midazolam premedication in children were evaluated in an ambulatory surgery unit. Eighty unmedicated children (ASA PS I or II, ages 1-6 yr) were randomly assigned to one of four groups receiving midazolam 0.5, 0.75, or 1.0 mg.kg-1 or a placebo 30 min before separation from parents. Heart rate, ...

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[Oral sedation with midazolam in blepharoplasty].

PURPOSE To evaluate the safety and usefulness of the use of oral sedation with midazolam (15 mg) in patients submitted to blepharoplasty. METHODS Randomized double-blind prospective study of 42 patients (surgical risk ASA I and II) divided into three groups of 14 patients each: Group M (midazolam 15 mg), group P (placebo) and group SM (no medication). All patients were evaluated according to ...

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Evaluation of oral midazolam as pre-medication in day care surgery in adult Pakistani patients.

A placebo controlled randomized double blind study was designed to assess the suitability of oral Midazolam as a premedication in day care surgery in adult Pakistani patients. Fifty ASA I and II patients aged between 20-60 years received either Midazolam 7.5 mg or a placebo approximately one hour prior to surgery. Midazolam 7.5 mg produced significant anxiolysis and sedation (p < 0.001) in comp...

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مقایسه ترکیب میدازولام کتامین با میدازولام و کتامین به تنهایی در بیهوشی اطفال، مرکز طبی کودکان، 1379

Anxiolysis and sedation with oral midazolam are common practice in pediatric anesthesia. Good or excellent results are seen in only 50% to 80% of cases, so we decided to investigate if addition of a low dose of oral ketamine to midazolam (ketamine2.5 mg /kg ^midazolam 0.25 mg/kg )resulted in better premedication compared with oral midazolam 0.5 mg/kg or ketamine 6 mg/kg alone.Methods and Materi...

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Randomized clinical trial of sedation with oral midazolam for voiding cystourethrography in Children

  Abstract   Background: Voiding Cystourethrography (VCUG) is a distressing procedure   for children. Conscious sedation with any drug that its dose would not influences the   procedure is preferred. The aim of this study was to assess the effectiveness of conscious sedation using oral midazolam in children undergoing VCUG.   Methods: From November 2008 to October 2009 period, 93 Patients (68 g...

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ژورنال

عنوان ژورنال: Anaesthesia and Intensive Care

سال: 1994

ISSN: 0310-057X,1448-0271

DOI: 10.1177/0310057x9402200507